• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

TC-A 2317 hydrochloride

CAS No. 1245907-03-2

TC-A 2317 hydrochloride ( —— )

产品货号. M27721 CAS No. 1245907-03-2

TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A with a Ki of 1.2 nM compared to Aurora kinase B with a Ki of 101 nM. TC-A 2317 hydrochloride shows antitumor activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TC-A 2317 hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A with a Ki of 1.2 nM compared to Aurora kinase B with a Ki of 101 nM. TC-A 2317 hydrochloride shows antitumor activity.
  • 产品描述
    TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A with a Ki of 1.2 nM compared to Aurora kinase B with a Ki of 101 nM. TC-A 2317 hydrochloride shows antitumor activity.(In Vivo):In rats, TC-A 2317 hydrochloride (30 mg/kg;p.o.) shows good PK profile; Cmax value is 4930 nM (Tmax=1.2 h) and serum concentration after 24 h is 52 nM (T1/2=3.3 h). In the antitumor mice model, TC-A 2317 hydrochloride is effective without a decrease of body weight.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    GluR
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1245907-03-2
  • 分子量
    392.9
  • 分子式
    C19H29ClN6O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.CC(CCCC(C)(C)O)Nc1nc(Nc2cc(C)[nH]n2)cc(C)c1[N+]#[C-]
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Hou X, et al. Superficial Chiral Etching on Achiral Metal-Organic Framework for Enantioselective Sorption. ACS Appl Mater Interfaces. 2017 Sep 20;9(37):32264-32269.
产品手册
关联产品
  • (S)-ErSO

    (S)-ErSO is an inactive dextrorotatory enantiomer of ErSO.

  • Gly-Arg-Gly-Asp-Ser ...

    Gly-Arg-Gly-Asp-Ser (GRGDS) is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion.

  • Methyl nomilinate

    Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.